Rapid Nerve Rescue

RESEARCH & TESTING

Rapid Nerve Rescue CBD Cream is the only cream on the market designed specifically for neuropathy patients.

What Is Rapid Nerve Rescue CBD Cream?

RNR (Rapid Nerve Rescue) is the only cream on the market designed specifically for neuropathy patients. The foundation for the cream is based on our experience successfully treating neuropathy for years. Dr. Thai has worked on the formulation for over 3 years now. The formula is based on interactions with the TRP family of receptors, activation of the endocannabinoid system, and cellular interaction of AAKG & Agamtine Sulfate. Using science and biology, this combination has proven successful in helping reduce & relieve neuropathic symptoms.

  • Doctor Developed & Patient Inspired
  • Clinically Tested with over 95% satisfaction rate
  • THC Free
  • Third Party Tested
  • 100% Money Back Guarantee for Wholesalers

  • Proprietary CBD Amino Acid Blend 
  • Only Specialized and Focused product on the market
  • Broad Spectrum
  • CO2 Extraction
  • USA Grown Hemp
RESULTS FROM OUR CLINICAL TESTING
  • 70% Noticed Immediate Results
  • 50% Experienced Reduction in Neuropathy Symptoms
  • 85% Reduced Their Pain Meds by 50%
  • 100% State They Choose Our Cream Over Their Pain Meds
Not All CBD Is Created Equally.

Did you know there was a study done by Penn State University that recently examined the amount of CBD that was on the label vs what was actually in the bottle? The results were astounding! It showed that 70% of the CBD extracts are either mislabeled or under labeled causing serious harm to its consumers. Due to the lack of regulation in this space you really have no idea what you are getting.

Our CBD cream contains the highest quality products to help relieve your body from the debilitating effects of neuropathy. Our CBD has been independently tested to assure that it is pure. We believe transparency and consistency should be put first and foremost when producing any product. All CBD raw materials and finished products have been third party tested by an ISO-17025 accredited lab to ensure purity, potency, and safety prior to release. You can review our Certificate of Analysis. Dr. Thai's Rapid Nerve Rescue is backed by a 100% satisfaction guarantee.

In addition to the third party testing, we have physically tested our product on neuropathy patients. To our knowledge, no other CBD product can make that claim.

The Science: How does Rapid Nerve Rescue CBD Cream work?

CBD has very potent anti-inflammatory and immunosuppressive properties. Inflammation is a complicated process involving many signaling pathways. The body uses signaling molecules called eicosanoids to initiate the inflammatory response.

One of the ways CBD can reduce inflammation is by inhibiting an eicosanoid enzyme called COX2. NSAID medications such as Advil and Aspirin also target COX2 in their method of action. Another thing CBD does is affects cytokines, which are important to the inflammation response. CBD reduces the effects of pro-inflammatory cytokines, thereby reducing inflammation. Studies have also shown that CBD decreases the transmigration of blood leukocytes by downregulating the expression of vascular cell adhesion molecule-1 (VCAM-1), chemokines (CCL2 and CCL5) and the proinflammatory cytokine IL-1β, as well as by attenuating the activation of microglia. Adenosine A2A receptors aid in some of the anti-inflammatory effects of CBD. My cream has 1200mg of CBD and a proprietary terpene blend as well as 2 amino compound derivatives to provide a therapeutic effect for patients with any type of neuropathic pain.

With people in pain, inflammation is the primary mechanism of action. By harnessing the CBD properties and using a topical cream to directly target the area of involvement, we have seen dramatic changes in patients' pain levels. This is why I chose a topical vs a tincture in my application. My main focus is to enhance the quality of life of my patients, and to enable them to deal with their pain in a safer and natural way. In my office we have tested over 300 patients with neuropathy and attached is my study and results.

How Can CBD Help Our Patients?

The main uses of CBD are to aid in the reductions of pain, inflammation, stress, anxiety, and as a sleep aid. CBD stimulates the regulatory system in our body called the endocannabinoid system. The endocannabinoid system regulates a lot of processes like our body temperature, our pH, and it helps regulate hormones. We have noticed that after about 3 days of consistent usage of CBD, that is when you can notice the system is activated. So, that also means that if you are not taking CBD consistently, you are not going to get the consistent benefits.

Determining the Effectiveness of Dr. Thai's Rapid Nerve Rescue CBD Cream for Patient's Neuropathic Symptoms

by Dr. Bao Thai, DC

ABSTRACT / INTRODUCTION

Neuropathy is a devastating condition that continues to affect more people around the world every year. The rise in cases is directly related to the increase in diabetes and poor lifestyle choices. Medication side effects and surgery induced neuropathy also accounts for the increase. The core cause of neuropathic symptoms is due to either axonal degeneration or myelin destruction, both of which are typically caused by neuro inflammation that occurs. My hypothesis is if you can consistently decrease the inflammation and decrease neuronal hypersensitivity at the site, that patients will experience a reduction in symptoms.

METHODS

The cream that was developed went through many rounds of reformulation. We decided upon 1500 mg of a high-quality CBD that was tested to have 0% THC. The dosage chosen was based on research studies. Then we combined the CBD with Agmatine Sulfate, Alpha-Ketoglutarate, and a proprietary terpene blend. The combination of the CBD, amino acids, and terpenes were determined by past studies to be a safe option for the treatment of neuropathic symptoms. Our study was comprised of 300 patient visits. These patients were all current patients receiving treatment for neuropathic symptoms. The patients were instructed to use the cream 3x a day - One application in the morning, afternoon, and at night. This was done over a 4-week time frame. Before use, the symptoms reported by the patients ranged from pain to numbness and tingling.

RESULTS

The outcome for our study was incredibly positive. Our patients reported that they all noticed at least a 50% reduction in symptoms with the use of our cream. 85% of the patients reported that they were able to reduce their use of pain meds completely or by half. 70% of the patients noticed an immediate change. 60% reported it took only 3 days of use to notice a significant change. 20% said it took 2 weeks of use to notice a significant change. It is worth to note that the patients that took 2 weeks for change all were very severe cases of neuropathy. 100% of patients reported that they would rather use the cream VS their prescription meds due to the side effects and lack of effectiveness. These initial findings are incredibly important as they provide evidence for the use in treating neuropathic symptoms without having negative side effects for patients.


Citation

Xu DH, Cullen BD, Tang M, Fang Y. The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities. Curr Pharm Biotechnol. 2020;21(5):390-402. doi: 10.2174/1389201020666191202111534. PMID: 31793418.

de Almeida DL, Devi LA. Diversity of molecular targets and signaling pathways for CBD. Pharmacol Res Perspect. 2020 Dec;8(6):e00682. doi: 10.1002/prp2.682. PMID: 33169541; PMCID: PMC7652785.

Philpott HT, O'Brien M, McDougall JJ. Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis. Pain. 2017 Dec;158(12):2442-2451. doi: 10.1097/j.pain.0000000000001052. PMID: 28885454; PMCID: PMC5690292.

Anand U, Jones B, Korchev Y, Bloom SR, Pacchetti B, Anand P, Sodergren MH. CBD Effects on TRPV1 Signaling Pathways in Cultured DRG Neurons. J Pain Res. 2020 Sep 11;13:2269-2278. doi: 10.2147/JPR.S258433. PMID: 32982390; PMCID: PMC7494392.

Gilad GM, Gilad VH. Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report. J Med Food. 2014 Nov;17(11):1256-9. doi: 10.1089/jmf.2014.0026. Epub 2014 Sep 23. PMID: 25247837.

Rosenberg ML, Tohidi V, Sherwood K, Gayen S, Medel R, Gilad GM. Evidence for Dietary Agmatine Sulfate Effectiveness in Neuropathies Associated with Painful Small Fiber Neuropathy. A Pilot Open-Label Consecutive Case Series Study. Nutrients. 2020 Feb 23;12(2):576. doi: 10.3390/nu12020576. PMID: 32102167; PMCID: PMC7071502.

Wax B, Kavazis AN, Webb HE, Brown SP. Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men. J Int Soc Sports Nutr. 2012 Apr 17;9(1):17. doi: 10.1186/1550-2783-9-17. PMID: 22510253; PMCID: PMC3428651.

Willoughby DS, Boucher T, Reid J, Skelton G, Clark M. Effects of 7 days of arginine-alpha-ketoglutarate supplementation on blood flow, plasma L-arginine, nitric oxide metabolites, and asymmetric dimethyl arginine after resistance exercise. Int J Sport Nutr Exerc Metab. 2011 Aug;21(4):291-9. doi: 10.1123/ijsnem.21.4.291. PMID: 21813912.


Continued Reference / Citation

Mecha M, Feliú A, Iñigo PM, Mestre L, Carrillo-Salinas FJ, Guaza C. Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: a role for A2A receptors. Neurobiol Dis. 2013 Nov;59:141-50. doi: 10.1016/j.nbd.2013.06.016. Epub 2013 Jul 11. PMID: 23851307.

Esraa Aly, Willias Masocha, Targeting the endocannabinoid system for management of HIV-associated neuropathic pain: A systematic review, IBRO Neuroscience Reports, 10.1016/j.ibneur.2021.01.004, 10, (109-118), (2021).

Igor Dykukha, Rolf Malessa, Ute Essner, Michael A Überall, Nabiximols in Chronic Neuropathic Pain: A Meta-Analysis of Randomized Placebo-Controlled Trials, Pain Medicine, 10.1093/pm/pnab050, 22, 4, (861-874), (2021).

Taurean Brown, DeLawrence Sykes, Antiño R. Allen, Implications of Breast Cancer Chemotherapy-Induced Inflammation on the Gut, Liver, and Central Nervous System, Biomedicines, 10.3390/biomedicines9020189, 9, 2, (189), (2021).

Dixon H. Xu, Benjamin D. Cullen, Meng Tang, Yujiang Fang, The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities, Current Pharmaceutical Biotechnology, 10.2174/1389201020666191202111534, 21, 5, (390-402), (2020).

VanDolah HJ, Bauer BA, Mauck KF. Clinicians' Guide to Cannabidiol and Hemp Oils. Mayo Clin Proc. 2019 Sep;94(9):1840-1851. doi: 10.1016/j.mayocp.2019.01.003. Epub 2019 Aug 22. PMID: 31447137.

Baron EP. Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science. Headache. 2018 Jul;58(7):1139-1186. doi: 10.1111/head.13345. PMID: 30152161.

Eskander JP, Spall J, Spall A, Shah RV, Kaye AD. Cannabidiol (CBD) as a treatment of acute and chronic back pain: A case series and literature review. J Opioid Manag. 2020 May/Jun;16(3):215-218. doi: 10.5055/jom.2020.0570. PMID: 32421842.

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